Pay in 4 interest-free payments of $30.00 Learn more
Ships within 48 hours · Estimated delivery Jul 26 - Jul 31
Z-IETD-FMK inhibits the cleavage of caspase-8 and only partially inhibits the cleavage of caspase-3 and PARP
Na/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9
23(41)16-51-36(46)39(3)10-9-38-2)14-19-26(22)32(45)28-27(30(19)43)29(42)18-7-6-8-21(48-4)25(18)31(28)44/h6-8
21(10):3838-3841
Phrixotoxin 3 TFA Catalog No.:M17683-C Z-IETD-FMK inhibits the cleavage ofPhrixotoxin 3 TFA is a potent blocker of voltage gated sodium channels, with IC50s of 0. 6, 42, 72, 288, 610 nM for NaV1. 2, NaV1. 3, NaV1. 4, NaV1. 1 and NaV1. 5, respectively. Phrixotoxin 3 TFA modulates voltage gated sodium channels with properties similar to those of typical gating modifier toxins, both by causing a depolarizing shift in gating kinetics and by blocking the inward component of the sodium current. Product information Molecular